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What is Mosquirix™?

Mosquirix™, also known as RTS,S, is an injectable malaria vaccine developed by GSK. GSK led the development of RTS,S over a 30-year period. In 2001, GSK began a collaboration with the PATH Malaria Vaccine Initiative (MVI) to continue developing RTS,S. An advanced clinical trials (referred to below as Phase 3 trials) to assess the vaccine’s efficacy and safety was conducted between 2009 and 2014 through a partnership that involved GSK, MVI (with support from the Bill & Melinda Gates Foundation) and a network of African research centres at 11 sites in 7 countries including Ghana.

MosquirixTM acts against Plasmodium falciparum, the most deadly malaria parasite globally, and the most prevalent in Ghana and the rest of sub-Saharan Africa. MosquirixTM offers no protection against Plasmodium vivax malaria, a strain of the malaria parasite which predominates in many countries outside of Africa.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.

Historically, vaccines have proved to be among the most effective means of preventing disease and saving lives, particularly in the case of infectious diseases. While malaria death rates in sub-Saharan Africa have dropped in recent years with the scale-up of existing malaria control measures, the disease continues to take a heavy toll: there were 212 million malaria cases worldwide in 2015 with 429,000 deaths. The majority of deaths are in children under the age of five, living in sub-Saharan Africa. In Ghana, malaria caused 2,133 deaths in 2015, approximately 51% of which afflict children under the age of five.